The type of skin infection depends on the depth and the skin compartment involved
For the majority of patients, empiric treatment is most often directed against gram-positive cocci [ 1, 6 ]
Nov 12, 2007 · Skin and soft tissue infections (SSTIs) are clinical entities of variable presentation, etiology and severity that involve microbial invasion of the layers of the skin and underlying soft tissues
8 mg TMP/kg/day PO divided q12hr for 7-14 days if serious infection ; 8-10 mg TMP/kg/day IV divided q6-12hr
Trimethoprim-sulfamethoxazole (TMP-SMX), also known as co-trimoxazole, is a combination of two antimicrobial agents that act synergistically against a
This medicine will not work
Treatment failure is
Skin and soft tissue infections (SSTIs) are clinical entities of variable presentation, etiology and severity that involve microbial invasion of the layers of the skin
120-180kg: 2 DS tablets PO q8h >180kg: 2 DS tablets PO q6h (Ideally ≥2
, penicillin derivatives, first- or second-generation clindamycin, change clindamycin to alternate active agent such as bactrim or doxycycline
The vast doxycycline, or clindamycin for the management of skin and soft tissue infections
In general, patients with all of the following characteristics can be managed as outpatients: no signs of sepsis, low suspicion of deep soft tissue infection including necrotizing fasciitis, and lack of exacerbation of
Causative organisms vary widely according to infection site, underlying conditions, but also from one region of the world to the other [4,15,16,17,18]
Pasteurella multocida is the most common cause of soft tissue infection in humans following bites or scratches from dogs and cats
Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America
Prevotella spp
The optimal treatment for purulent infections such as boils and carbuncles is incision and drainage
The most common bacterial causes of skin and soft tissue infections (SSTI) are group A Streptococcus (GAS) and Staphylococcus aureus, the key bacterial agents of impetigo, cellulitis, abscesses, and wound infections []
The general principles of antimicrobial treatment of infections caused by P
cellulitis, post-surgical infections) to the immediately life threatening
Although other combinations of sulfonamides are available with trimethoprim, TMP-SMX is by far the most widely used
The role of sulfamethoxazole-trimethoprim (SXT) in SSTI treatment, particularly when group A Streptococcus (GAS) is involved, is controver
Amongst the broad spectrum of skin and soft tissue infections treatment is mainly